Indications for use: Treatment of such diseases in adults as:
- cryptococcal meningitis;
- coccidioidosis;
- invasive candidiasis;
- candidiasis of the mucous membranes, including candidiasis of the oropharynx and esophageal candidiasis, candiduria, chronic candidiasis of the skin and mucous membranes;
- chronic atrophic candidiasis (candidiasis caused by the use of dentures), when local dental hygiene products are ineffective;
- vaginal candidiasis, acute or recurrent, when local therapy is not appropriate;
- candidal balanitis, when local therapy is not appropriate;
- dermatomycoses, including mycosis of the feet, mycosis of the smooth skin, inguinal dermatomycosis, lichen planus, and candidal infections of the skin, when systemic therapy is indicated;
- dermatophytic onychomycosis, when the use of other drugs is not appropriate.

Contraindication:
- Hypersensitivity to fluconazole, other azole compounds or any of the excipients of the drug.
- Simultaneous use of fluconazole and terfenadine in patients who use fluconazole repeatedly in doses of 400 mg/day and above (according to the results of the study of the interaction of multiple use).
- Concomitant use of fluconazole and other drugs that prolong the QT interval and are metabolized by the enzyme CYPZA4 (for example, cisapride, astemizole, pimozide, quinidine, amiodarone, and erythromycin).